Research Interest

Our laboratory employs genomic and computational biology approaches to investigate the molecular mechanisms of development and diseases systematically. We are committed to developing innovative functional genomics and single-cell omics technologies and applying them to identify novel drug targets and biomarkers. We excel in bioinformatics analysis, data science, and in vivo gene engineering using lipid nanoparticles.

Specific research directions include:

    1. Mechanisms of action and resistance of immune checkpoint blockade

    2. Identification of novel drug targets and biomarkers

    3. In vivo CAR-T cell therapy

Several positions are available, and we welcome young scholars to join us!

Website: https://bioinfo.westlake.edu.cn/index.htm

Contact: wangxi@westlake.edu.cn

本实验室运用基因组学和计算生物学方法，系统研究生命过程和疾病的分子机制。我们致力于开发创新型功能基因组学和单细胞组学技术及分析方法，并将其应用于新药靶点和生物标志物的开发。我们擅长生物信息学整合分析、数据挖掘和基于脂质纳米颗粒的体内基因工程改造。

具体研究方向包括：

1. 肿瘤药物的作用机理和抗性机制

2. 鉴定肿瘤新药靶点和生物标志物

3. 体内CAR-T细胞治疗

现有多个职位虚位以待，希望有志于原创性研究的青年学者加盟一起探索生命的规律！

实验室网站：https://bioinfo.westlake.edu.cn/index.htm

联系方式：wangxi@westlake.edu.cn